Grupo de Investigación

Fecha de Creación -  01 de Mayo de 2000
Código Colciencias -  COL0021318
Clasificación Colciencias - (Convocatoria 833 de 2018): C
Ubicación -  Campus El Bosque, Facultad de Ciencias de la Salud. Campus El Bosque. Calle 157 No. 19-55. Conmutador 6399151 Ext 516. Telefax: 6781080. Email. chicamocha@unab.edu.co

Contacto

Investigadores

Enlace a Colciencias Semilleros Asociados

Presentación

To evaluate strategies to prevent, diagnose, and treat risk factors for the development of atherothrombotic events.

Líneas de Investigación

  • Chagas’ disease

    Líder de la línea: Juan Carlos Villar Centeno

    To contribute to bridge the knowledge gap in the areas of diagnosis and preventions of the acute and indeterminate phases of Chagas’ disease.

    Milestones: a) Assembly and follow-up of the CHICAMOCHA cohort (n ~ 400 asymptomatic adults, seropositive for T.cruzi, evaluated for changes in cardiovascular function at 2 and 4 years) aimed at determining prognostic factors in Chagas’ disease; b) Conduction of RCTs (n ~ [250 - 500]) to evaluate the efficacy of trypanocidal and combined therapy (trypanocidal and neurohormonal) to reduce the risk of progression from the indeterminate to the chronic phase of Chagas’ disease.

  • Cardiovascular Health

    Líder de la línea: Juan Carlos Villar Centeno

    To estimate the incidence and monitor the change of health behaviours and factors that constitute the construct of “cardiovascular health” and to determine its association to atherothrombotic events. Milestones: Assembly and follow-up of the CHICAMOCHA cohort (n ~ 1,200 asymptomatic adults, seronegative for T.cruzi, evaluated for changes of cardiovascular health at 12 years).

  • Cardiovascular complications related to surgical procedures

    Líder de la línea: Juan Carlos Villar Centeno

    To estimate the incidence of cardiovascular complications and to determine prognostic factors among patients undergoing cardiac and non-cardiac surgical procedures.  Milestones: a) Coordination of recruitment centers in Colombia for the PeriOperative ISchemic Evaluation Trials (POISE-1 and POISE-2) and the Steroids In caRdiac Surgery Trial (SIRS Trial); b) Coordination of recruitment centers in Bucaramanga for the Myocardial Injury After Noncardiac Surgery (MANAGE), Left Atrial Appendage Occlusion Study III (LAAOS III), and the Transfusion requirements in cardiac surgery III (TRICS III); c) Coordination of recruitment centers in Colombia for Vascular events in noncardiac surgery patients cohort evaluation (VISION).

  • Environmental determinants of cardiovascular disease

    Líder de la línea: Víctor Mauricio Herrera Galindo

    To estimate the exposure to air pollution (outdoor and indoor) and to determine its association to the development and progression of cardiovascular disease. Milestones: a) Conduction of a cross-sectional study to estimate the exposure to fine particulate matter (mass and composition) and their association to blood pressure among non-smoker adults in Bucaramanga (n ~ 500); b) Conduction of a pilot study  (n ~ 80) to characterize the exposure to air pollution related to different patterns of vehicle traffic and its association to markers of inflammation and cardiovascular function.